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CASorganic LLC - Your partner in biochemical's industry

 

CasOrganic's US Corporation offers versitile biochemicals and fine chemicals, peptide reagents which include coupling reagents, N-protecting reagents and miscellaneous compounds that might be used in amide bond formation. In recent years, peptide coupling reactions have been significantly advanced in accord with the development of new peptide coupling reagents in organic synthesis. Research and development of new peptide coupling reagents has been steadily accelerated in the past few years. Moreover, tremendously expanded applications have been possible to new and broad synthetic challenges. Among many, coupling reagents responsible for the formation of azide, mixed anhydride, and acid halide intermediates have gained substantial popularity in peptide coupling reactions. DCC as a peptide-coupling reagent has particularly attracted organic chemists in their synthesis of complex molecules. Moreover, the development of onium-type coupling reagents has made the incorporation of non-coded or sterically hindered amino acids including N-methylated and a,a-dialkylated amino acids smoothly into the corresponding peptides possible.

 

Featured Products

 

Phosphonium reagents

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Chloroformate, pyridinium and other coupling reagents

Racemisation suppressants

 

Peptide coupling agent for sterically hindered amino acids which are not reactive with carbodiimide-based coupling agents
Product Description
Product Name
BOP-Cl
Structure
IUPAC Name, Synonims
bis(2-oxo-3-oxazolidinyl)-phosphinicchlorid
PHOSPHORIC ACID BIS(2-OXOOXAZOLIDIDE) CHLORIDE
N,N-BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHINIC CHLORIDE
N,N-BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHONIC CHLORIDE
N,N-BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHORODIAMIDIC CHLORIDE
BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHINIC CHLORIDE
BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHONIC CHLORIDE
BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHORODIAMIDIC CHLORIDE
BOP-CI
BOP-CL
BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHINIC CHLORIDE (BOP-CL)
N,N-BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHORAMIDIC CHLORIDE
BOP-CL BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHINIC CHLORIDE
Bis-(2-oxo-3-oxazolidinyl)-phosphinyl chloride
BOP-Cl, Phosphoric acid bis(2-oxooxazolidide) chloride
3-[Chloro-(2-oxo-1,3-oxazolidin-3-yl)phosphoryl]-1,3-oxazolidin-2-one
BOP-C
BOPDC
3,3'-(Chlorophosphinylidene)bis(oxazolidine-2-one)
3,3'-(Chlorophosphonoyl)bis(oxazolidine-2-one)
3,3'-(Oxochlorophosphoranylidene)bis(oxazolidine-2-one)
3,3'-Chlorophosphinylidenebis(oxazolidine-2-one)
Bis(2-oxo-3-oxazolidinyl)chlorophosphine oxide
Bis(2-oxo-3-oxazolidinyl)phosphinic acidchloride
CAS No
68641-49-6
Molecular Formula
C6H8ClN2O5P
Molecular Weight
254.57
Appearance
White crystalline powder
Melting Point
191-194 °C
Purity
>98%
Loss on dryging
---
Heavy metals
---
Packing
1kg; 25kg; 50kg
References
1. J. Cabré, A.L. Palomo Synthesis, 413, (1984)
2. S. Danishefsky et al Tetrahedron Lett. 25, 4203, (1984)
3. E.J. Corey et al. J. Am. Chem. Soc. 104, 6818, (1982) Chem. Soc. 104, 6818, (1982) 4. R.D. Tung, D.H. Rich J. Am. Chem. Soc. 107, 4342, (1985)