CASorganic LLC


USA

200 Village Road

Morganville, NJ 07751

Tel: (732) 677 05 50

Fax: (732) 970 34 84

www.casorganic.com

sales@casorganic.com

casorganic@gmail.com


CASorganic LLC - Your partner in biochemical's industry


 

CasOrganic's US Corporation offers versitile biochemicals and fine chemicals, peptide reagents which include coupling reagents, N-protecting reagents and miscellaneous compounds that might be used in amide bond formation. In recent years, peptide coupling reactions have been significantly advanced in accord with the development of new peptide coupling reagents in organic synthesis. Research and development of new peptide coupling reagents has been steadily accelerated in the past few years. Moreover, tremendously expanded applications have been possible to new and broad synthetic challenges. Among many, coupling reagents responsible for the formation of azide, mixed anhydride, and acid halide intermediates have gained substantial popularity in peptide coupling reactions. DCC as a peptide-coupling reagent has particularly attracted organic chemists in their synthesis of complex molecules. Moreover, the development of onium-type coupling reagents has made the incorporation of non-coded or sterically hindered amino acids including N-methylated and a,a-dialkylated amino acids smoothly into the corresponding peptides possible.

 

Featured Products

 

Phosphonium reagents

Uronium reagents

Immonium reagents

Carbodiimide reagents

Imidazolium reagents

Organophosphorous reagents

Acid halogenating reagents

Chloroformate, pyridinium and other coupling reagents

Racemisation suppressants

 

Additive used in the carbodiimide method for improved amidations1 and peptide couplings [2].
Used to activate a carboxyl group for amide bond formation [3,4].
Product Description
Product Name
HOSu
Structure
IUPAC Name, Synonims
N-HYDROXY-2,5-PYRROLIDINEDIONE
NHS
N-HYDROXYSUCCINIMDE
N-HYDROXYSUCCINIMIDE
N-HYDROXYSUCCINIMIDE POLYMER-BOUND
1-hydroxy-5-pyrrolidinedione
1-Hydroxysuccinimide
5-Pyrrolidinedione,1-hydroxy-2
Hydroxysuccinimide
Succinimide, N-hydroxy-
4-HYDROXY-2,5-PYRROLIDINEDIONE
2,5-PYRROLIDINEDIONE, 1-HYDROXY-
1-HYDROXY-2,5-PYRROLIDINEDIONE
1-HYDROXY-PYRROLIDINE-2,5-DIONE
HONSU
HOSU
HOSu~1-Hydroxy-2,5-pyrrolidinedione
N-Hydroxysuccinimide (HOSu)
N-HYDROXYSUCCINAMIDE
Hosu,Nhs(N-Hydroxysuccinimide)
9,10-Bis(Phenthynyl)Anthracene
HOSU (N-Hydroxysuccinimide)
NHS N-HYDROXYSUCCINIMIDE,
NHS OR HONSU
N-HYDOXYSUCCINIMIDE, NHS
HOSU (N-HYDROXYSUCCINIMIDE,NHS)
N-Hydroxysuccinimide >97%
N-HYDROXYSUCCINIMIDE pure
1-Hydroxy-2,5-pyrrolidinedione, HOSu
N-Hydroxysuccinic acid imide
Succinimidyl alcohol
CAS No
6066-82-6
Molecular Formula
C4H5NO3
Molecular Weight
115.09
Refractive index
 
Density
Appearance
White crystalline powder
Melting Point
92-94 ℃
Purity
>98%
Loss on dryging
<0.5%
Heavy metals
<25ppm
Packing
1kg; 25kg; 50kg
References
1. Anal. Biochem. 218, 87, (1994)
2. Polycyclic Aromat. Compd. 3, 781, (1993)
3. J. Am. Chem. Soc. 128, 15072, (2006)
4. J. Pept. Sci. 12, 653, (2006)