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CASorganic LLC - Your partner in biochemical's industry

 

CasOrganic's US Corporation offers versitile biochemicals and fine chemicals, peptide reagents which include coupling reagents, N-protecting reagents and miscellaneous compounds that might be used in amide bond formation. In recent years, peptide coupling reactions have been significantly advanced in accord with the development of new peptide coupling reagents in organic synthesis. Research and development of new peptide coupling reagents has been steadily accelerated in the past few years. Moreover, tremendously expanded applications have been possible to new and broad synthetic challenges. Among many, coupling reagents responsible for the formation of azide, mixed anhydride, and acid halide intermediates have gained substantial popularity in peptide coupling reactions. DCC as a peptide-coupling reagent has particularly attracted organic chemists in their synthesis of complex molecules. Moreover, the development of onium-type coupling reagents has made the incorporation of non-coded or sterically hindered amino acids including N-methylated and a,a-dialkylated amino acids smoothly into the corresponding peptides possible.

 

Featured Products

 

Phosphonium reagents

Uronium reagents

Immonium reagents

Carbodiimide reagents

Imidazolium reagents

Organophosphorous reagents

Acid halogenating reagents

Chloroformate, pyridinium and other coupling reagents

Racemisation suppressants

 

Additive which suppresses racemization in peptide synthesis [1,2]; Synthesis of amino acid active esters used as self-indicating building blocks in solid-phase synthesis [3,4].
Product Description
Product Name
HOOBt
Structure
IUPAC Name, Synonims
3-HYDROXY-4-KETOBENZOTRIAZINE
3-HYDROXY-3,4-DIHYDRO-4-OXO-1,2,3-BENZOTRIAZINE
3-HYDROXY-[1,2,3]BENZOTRIAZIN-4(3H)-ON
3-HYDROXY-1,2,3-BENZOTRIAZIN-4(3H)-ONE
3-HYDROXY-1,2,3-BENZOTRIAZIN-4-ONE
3-HYDROXY-1,2,3-BENZOTRIAZINE 4(3H)-ONE
3-HYDROXY-4-OXO-3,4-DIHYDRO-1,2,3-BENZOTRIAZINE
3,4-DIHYDRO-3-HYDROXY-4-OXO-(1,2,3)-BENZOTRIAZIN
3,4-DIHYDRO-3-HYDROXY-4-OXO-1,2,3-BENZOTRIAZINE
LABOTEST-BB LT00453576
HODHBT
HOOBT
hydroxy-3,4-dihydro-4-oxo-1,2,3-benzotriazine
DHOBT
DHBT
ODHBT
OXOHYDROXYBENZOTRIAZOLE
3 4-DIHYDRO-3-HYDROXY-4-OXO-1 2 3- &
3-Hydroxy-1,2,3-benzotriazine-4(3H)-one solution, 25% in DMF
3,4-Dihydro-3-Hydroxy-oxo-1,2,3-Benzotriazine
Hoobt(3-Hydroxy-1,2,3-Benzotriazin-4(3H)-One)
3,4-Dihydro-3-hydroxy-4-oxo-1,2,3-benzotriazine, 98+%
HOOBT (3-Hydroxy-1,2,3-benzotruazin-4(3H)-one)
HOOBt, DHBT
HODHBT (DHBT)
3,4-DIHYDRO-3-HYDROXY-4-OXO-1,2,3-BENZOTRIAZINE (DHBT)
3,4-DIHYDRO-3-HYDROXY-4-OXO-1,2,3-BENZOTRIAZINE (DHOBT) (DHBT) extrapure
3-Hydroxy-1,2,3-benzotriazin-4(3H)-one solution
3,4-Dihydro-3-hydroxy-4-oxo-1,2,3-benzotriazine, 3-Hydroxy-3,4-dihydro-4-oxo-1,2,3-benzotriazine, DHBT
3,4-Dihydro-3-hydroxy-4-oxo-benzotriazine
3-Hydroxy-3,4-dihydro-1,2,3-benzotriazine-4-one
CAS No
28230-32-2
Molecular Formula
C7H5N3O2
Molecular Weight
163.1
Refractive index
  
Density
Appearance
Off-white to white crystal powder
Melting Point
185-190 ℃ (dec.)
Purity
>98%
Loss on dryging
<0.5%
Heavy metals
<25ppm
Packing
1kg; 25kg; 50kg
References
1. W. König, R. Geiger Chem. Ber. 103, 2024, (1970)
2. Y. Kurano et al. J. Chem. Soc., Chem. Commun., 323, (1987)
3. E. Atherton et al. J. Chem. Soc. Perkin Trans. I, 2887, (1988)
4. L.R. Cameron et al. J. Chem. Soc. Perkin Trans. I, 2895, (1988)